{"id":149,"date":"2020-02-23T17:11:56","date_gmt":"2020-02-23T22:11:56","guid":{"rendered":"https:\/\/www.hydroassoc.org\/?p=149"},"modified":"2025-11-05T09:05:51","modified_gmt":"2025-11-05T14:05:51","slug":"epilepsy-and-hydrocephalus","status":"publish","type":"post","link":"https:\/\/www.hydroassoc.org\/epilepsy-and-hydrocephalus\/","title":{"rendered":"Essential Facts About Epilepsy and Hydrocephalus"},"content":{"rendered":"<h2>Epilepsy and Hydrocephalus: Understanding the Connection<\/h2>\n<p>Epilepsy is common in people with hydrocephalus. Of individuals with shunted hydrocephalus, an estimated 20% have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9881801\" target=\"_blank\" rel=\"noopener noreferrer\">Klepper et al., 1998<\/a>). <strong>Epilepsy<\/strong> is a brain disorder that causes unprovoked, recurring seizures. A person experiences a <strong>seizure<\/strong> when there is excessive and abnormal brain cell activity. This often produces uncontrolled movements, decreased responsiveness, and\/or unconsciousness.<\/p>\n<p>In the United States, it is estimated that 1.2% of the population has epilepsy (Zack &amp; Kobau, 2017). For people with shunted hydrocephalus, the risk of having epilepsy is related to the type or cause of hydrocephalus and to complications of its treatment.<\/p>\n<div class=\"su-box su-box-style-default\" id=\"\" style=\"border-color:#007595;border-radius:4px;max-width:none\"><div class=\"su-box-title\" style=\"background-color:#22a8c8;color:#FFFFFF;border-top-left-radius:2px;border-top-right-radius:2px\"><b>Webinar<\/b><\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:2px;border-bottom-right-radius:2px\"><a href=\"https:\/\/us02web.zoom.us\/rec\/share\/MpUxKZd2kpt_L7VuoX_1lWoBJfsv_2KgR6apq3572bk73zg1pv6GCvdCaMBYHmMu.Dx0vFfjhG994M3zB\" target=\"_blank\" rel=\"noopener\">Understanding Seizures and Epilepsy in Hydrocephalus: Risks, Triggers, and First Aid<\/a><\/div><\/div>\n<hr \/>\n<h2>How Common Is Epilepsy in People With Hydrocephalus?<\/h2>\n<p>Past studies have shown:<\/p>\n<ul>\n<li>4.5% of people with <a href=\"\/about-normal-pressure-hydrocephalus\/\">normal pressure hydrocephalus (NPH)<\/a> have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28885121\" target=\"_blank\" rel=\"noopener noreferrer\">Larsson et al., 2017<\/a>).<\/li>\n<li>11% of children with spina bifida and hydrocephalus have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17357034\" target=\"_blank\" rel=\"noopener\">Persson et al., 2006<\/a>).<\/li>\n<li>Up to 35% of children with <a href=\"\/congenital-hydrocephalus\/\">congenital hydrocephalus<\/a> (diagnosed before or at birth) have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2464773\" target=\"_blank\" rel=\"noopener noreferrer\">Persson et al., 2006; Fernell et al., 1988<\/a>).<\/li>\n<li>44-70% of children with posthemorrhagic hydrocephalus of prematurity have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27050777\" target=\"_blank\" rel=\"noopener noreferrer\">Battaglia et al., 2005; Tully et al., 2016<\/a>).<\/li>\n<\/ul>\n<hr \/>\n<h2>Does Shunt Placement Affect Epilepsy Risk?<\/h2>\n<p>Some studies have compared the rates of epilepsy before and after shunt placement. Studies suggest that shunt placement is associated with epilepsy; however, this may be because individuals with more severe hydrocephalus are more likely to get shunted and also to have epilepsy (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28885121\" target=\"_blank\" rel=\"noopener noreferrer\">Larsson et al., 2017; Tully et al., 2016; Bourgeois et al., 1999<\/a>). Factors that alter the risk for developing epilepsy include the presence of a brain malformation (excluding Chiari II), repeated brain surgeries, and surgical infection (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9950498\" target=\"_blank\" rel=\"noopener noreferrer\">Tully et al., 2016; Bourgeois et al., 1999<\/a>).<\/p>\n<hr \/>\n<h2>Factors That Increase Seizure Risk in Hydrocephalus<\/h2>\n<p>Past studies have shown:<\/p>\n<ul>\n<li>Surgical infection may double the risk of developing seizures (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27050777\" target=\"_blank\" rel=\"noopener noreferrer\">Tully et al., 2016<\/a>).<\/li>\n<li>Children who have been shunted for hydrocephalus and who have a significant cognitive delay or motor disability are more likely to develop seizures than those without cognitive or motor delays (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9579862\" target=\"_blank\" rel=\"noopener noreferrer\">Hoppe-Hirsch et al., 1998<\/a>; <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9950498\" target=\"_blank\" rel=\"noopener noreferrer\">Bourgeois et al., 1999<\/a>).<\/li>\n<li>Seizures are not likely to occur at the time of shunt malfunction (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8933565\" target=\"_blank\" rel=\"noopener noreferrer\">Johnson et al., 1996<\/a>).<\/li>\n<\/ul>\n<hr \/>\n<h2>When Epilepsy Surgery Leads to Hydrocephalus<\/h2>\n<p>The relationship between hydrocephalus and epilepsy can also work in the other direction: Some patients with epilepsy who undergo a surgical procedure called functional hemispherectomy develop hydrocephalus as a consequence of the surgery. A significant portion of these patients develop hydrocephalus on a delayed basis, indicating the need for long-term surveillance (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23106378\" target=\"_blank\" rel=\"noopener noreferrer\">Lew et al., 2013<\/a>).<\/p>\n<p>Most children and adults with hydrocephalus and epilepsy take medication to control the seizures; however, approximately 30% of patients fail to respond to drug treatment (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9950498\" target=\"_blank\" rel=\"noopener noreferrer\">Bourgeois et al., 1999<\/a>). This is similar to the epileptic population in general (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24980390\" target=\"_blank\" rel=\"noopener noreferrer\">Laxer et al., 2014<\/a>; <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10660394\" target=\"_blank\" rel=\"noopener noreferrer\">Kwan &amp; Brodie, 2000<\/a>). For these patients, surgical management of epilepsy may be an option.<\/p>\n<hr \/>\n<p>For more information on epilepsy\/seizures and hydrocephalus, follow the links provided in the text.<br \/>\nFor additional support and educational resources, we encourage you to contact the <a href=\"https:\/\/www.epilepsy.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">Epilepsy Foundation<\/a>\u00a0or the <a href=\"https:\/\/www.brainrecoveryproject.org\/hydrocephalus\/\" target=\"_blank\" rel=\"noopener noreferrer\">Brain Recovery Project<\/a>.<\/p>\n<hr \/>\n<p><em>This article is designed to provide helpful information on the subjects discussed. It is not intended as a substitute for treatment advice from a medical professional. For diagnosis or treatment of any medical condition, consult your doctor.<\/em><\/p>\n\r\n            <div id=\"daexthefup-container\"\r\n                 class=\"daexthefup-container daexthefup-layout-stacked daexthefup-alignment-center\"\r\n                 data-post-id=\"149\">\r\n\r\n                <div class=\"daexthefup-feedback\">\r\n                    <div class=\"daexthefup-text\">\r\n                        <h3 class=\"daexthefup-title\">Was this resource helpful?<\/h3>\r\n                    <\/div>\r\n                    <div class=\"daexthefup-buttons-container\">\r\n                        <div class=\"daexthefup-buttons\">\r\n\t\t\t\t\t\t\t\r\n            <div class=\"daexthefup-yes daexthefup-button daexthefup-button-type-text\" data-value=\"1\">\r\n                <div class=\"daexthefup-button-text\">Yes<\/div>\r\n            <\/div>\r\n\r\n\t\t\t\t\t\t\t\t\t\t\r\n            <div class=\"daexthefup-no daexthefup-button daexthefup-button-type-text\" data-value=\"0\">\r\n                <div class=\"daexthefup-button-text\">No<\/div>\r\n            <\/div>\r\n\r\n\t\t\t                        <\/div>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n                <div class=\"daexthefup-comment\">\r\n                    <div class=\"daexthefup-comment-top-container\">\r\n                        <label id=\"daexthefup-comment-label\" class=\"daexthefup-comment-label\"><\/label>\r\n\t\t\t\t\t\t                            <div class=\"daexthefup-comment-character-counter-container\">\r\n                                <div id=\"daexthefup-comment-character-counter-number\"\r\n                                     class=\"daexthefup-comment-character-counter-number\"><\/div>\r\n                                <div class=\"daexthefup-comment-character-counter-text\"><\/div>\r\n                            <\/div>\r\n\t\t\t\t\t\t                    <\/div>\r\n                    <textarea id=\"daexthefup-comment-textarea\" class=\"daexthefup-comment-textarea\"\r\n                              placeholder=\"Type your message\"\r\n                              maxlength=\"400\"><\/textarea>\r\n                    <div class=\"daexthefup-comment-buttons-container\">\r\n                        <button class=\"daexthefup-comment-submit daexthefup-button\">Submit<\/button>\r\n                        <button class=\"daexthefup-comment-cancel daexthefup-button\">Cancel<\/button>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n                <div class=\"daexthefup-successful-submission-text\">Thanks for your feedback!<\/div>\r\n\r\n            <\/div>\r\n\r\n\t\t\t","protected":false},"excerpt":{"rendered":"<p>Epilepsy is common in people with hydrocephalus. Of individuals with shunted hydrocephalus, an estimated 20% have epilepsy<\/p>\n","protected":false},"author":6,"featured_media":36648,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_helpful_pro_status":1,"_searchwp_excluded":"","inline_featured_image":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4,1182,1128,1207],"tags":[1214],"post_folder":[9],"class_list":["post-149","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article","category-rating","category-related-conditions","category-resources","tag-related-conditions"],"acf":[],"jetpack_featured_media_url":"https:\/\/www.hydroassoc.org\/wp-content\/uploads\/2020\/02\/Ft-Image-for-Blogs-and-SYS-300x240-7.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts\/149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/comments?post=149"}],"version-history":[{"count":0,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts\/149\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/media\/36648"}],"wp:attachment":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/media?parent=149"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/categories?post=149"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/tags?post=149"},{"taxonomy":"post_folder","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/post_folder?post=149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}