{"id":27742,"date":"2024-06-25T00:00:00","date_gmt":"2024-06-25T04:00:00","guid":{"rendered":"https:\/\/www.hydroassoc.org\/research-101-the-importance-of-sample-size\/"},"modified":"2024-10-25T13:30:01","modified_gmt":"2024-10-25T17:30:01","slug":"research-101-the-importance-of-sample-size","status":"publish","type":"post","link":"https:\/\/www.hydroassoc.org\/research-101-the-importance-of-sample-size\/","title":{"rendered":"Research 101: The Importance of Sample Size"},"content":{"rendered":"\n\n\t<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/uploads\/2015\/04\/SampleSize.jpg\" alt=\"Sample Size in Hydrocephalus Research Studies\" width=\"380\" height=\"190\" \/>In the <strong>Research 101 blog series<\/strong>, we have discussed <a href=\"https:\/\/www.hydroassoc.org\/research-101-an-explanation-of-clinical-trials-design\/\" target=\"_blank\" rel=\"noopener\" data-feathr-click-track=\"true\" data-feathr-link-aids=\"5e8f8cf0d4f6e391de55d8ee\">how clinical trials are designed<\/a> and the strengths and weaknesses of these designs. One factor that can derail or strengthen any study is Sample Size.<\/p>\n<p>So, what is <strong>Sample Size<\/strong>? Very simply stated, sample size is the number of people participating in a <strong>study<\/strong>. The more people that participate, the better the study is. Having a large number of participants reduces the risk of accidentally having extreme, or biased, groups &#8211; such as having all adults or all children in a study that should have equal numbers of adults and children.<\/p>\n<h2>Let&#8217;s find out why:<\/h2>\n<p>Pretend that we have a jar with blue and white marbles. The jar represents our entire population. Half of the marbles are <strong>White <\/strong>and half are <strong>Blue<\/strong>.<\/p>\n<p><strong>White<\/strong> marbles = adults = \u00bd of the population is adults<\/p>\n<p><strong>\u00a0 \u00a0 Blue<\/strong> marbles = children = \u00bd of the population is children<\/p>\n<p>We want a representative sample of people in our study &#8211; so ideally we want half of the participants to be adults and half to be children. Unfortunately, we decide that we only need 3 people in our study<\/p>\n<p><strong>\u00a0We pick 3 people at random (sample size = 3)<\/strong><\/p>\n<img decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/plugins\/advanced-wp-columns\/assets\/js\/plugins\/views\/img\/1x1-pixel.png\" alt=\"\">\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/uploads\/2015\/04\/15_06_18-Research-101-Sample-Size-e1435247853120.jpg\" alt=\"Jar representing sample size in research studies\" width=\"244\" height=\"296\" \/><\/p>\n<img decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/plugins\/advanced-wp-columns\/assets\/js\/plugins\/views\/img\/1x1-pixel.png\" alt=\"\">\n<p>There are <strong>4 possible color combinations<\/strong>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/uploads\/2015\/06\/ColorCombos.jpg\" alt=\"Possible combinations in research samples\" width=\"450\" height=\"115\" \/><\/p>\n<p>&nbsp;<\/p>\n<img decoding=\"async\" src=\"https:\/\/www.hydroassoc.org\/wp-content\/plugins\/advanced-wp-columns\/assets\/js\/plugins\/views\/img\/1x1-pixel.png\" alt=\"\">\n<h2><br \/>We need to come up with a better plan<\/h2>\n<p>After looking at the odds of randomly picking an extreme, non-representative group, we decide that we need a much bigger sample size.\u00a0 This time, we are going to choose 50 people to be in our study (sample size = 50). With a sample size of 50, there are 51 possible combinations of Blue and White marbles.<\/p>\n<p>When 50 people are randomly chosen, there is only a <strong>3.9% chance of having an<\/strong> <strong>extreme group<\/strong> composed of either all adults (White) or all children (Blue).\u00a0 Therefore, we are likely to pick a group that is more representative of our population.<\/p>\n<p>This is a simple example illustrating one-way sample size is important for research studies. In real-life situations, many issues associated with extreme, or biased, groups can be avoided by increasing the number of people in each group.<\/p>\n<h5>Other entries in our Research 101 Blog Series with Dr. Koschnitzky:<\/h5>\n<p><a href=\"\/research-101-an-explanation-of-clinical-trials-design\/\" data-feathr-click-track=\"true\" data-feathr-link-aids=\"5e8f8cf0d4f6e391de55d8ee\">Research 101: An Explanation of Clinical Trials Design<\/a><\/p>\n<p><a href=\"\/research-101-randomization\/\" data-feathr-click-track=\"true\" data-feathr-link-aids=\"5e8f8cf0d4f6e391de55d8ee\">Research 101: Randomization<\/a><\/p>\n<p><a href=\"\/research-101-junction-junction-whats-your-function\/\" data-feathr-click-track=\"true\" data-feathr-link-aids=\"5e8f8cf0d4f6e391de55d8ee\">Research 101: Junction, Junction, What&#8217;s Your Function?<\/a><\/p>\n<p><a href=\"\/research-101-generalizability\/\" data-feathr-click-track=\"true\" data-feathr-link-aids=\"5e8f8cf0d4f6e391de55d8ee\">Research 101: Generalizability<\/a><\/p>\n\n\r\n            <div id=\"daexthefup-container\"\r\n                 class=\"daexthefup-container daexthefup-layout-stacked daexthefup-alignment-center\"\r\n                 data-post-id=\"27742\">\r\n\r\n                <div class=\"daexthefup-feedback\">\r\n                    <div class=\"daexthefup-text\">\r\n                        <h3 class=\"daexthefup-title\">Was this resource helpful?<\/h3>\r\n                    <\/div>\r\n                    <div class=\"daexthefup-buttons-container\">\r\n                        <div class=\"daexthefup-buttons\">\r\n\t\t\t\t\t\t\t\r\n            <div class=\"daexthefup-yes daexthefup-button daexthefup-button-type-text\" data-value=\"1\">\r\n                <div class=\"daexthefup-button-text\">Yes<\/div>\r\n            <\/div>\r\n\r\n\t\t\t\t\t\t\t\t\t\t\r\n            <div class=\"daexthefup-no daexthefup-button daexthefup-button-type-text\" data-value=\"0\">\r\n                <div class=\"daexthefup-button-text\">No<\/div>\r\n            <\/div>\r\n\r\n\t\t\t                        <\/div>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n                <div class=\"daexthefup-comment\">\r\n                    <div class=\"daexthefup-comment-top-container\">\r\n                        <label id=\"daexthefup-comment-label\" class=\"daexthefup-comment-label\"><\/label>\r\n\t\t\t\t\t\t                            <div class=\"daexthefup-comment-character-counter-container\">\r\n                                <div id=\"daexthefup-comment-character-counter-number\"\r\n                                     class=\"daexthefup-comment-character-counter-number\"><\/div>\r\n                                <div class=\"daexthefup-comment-character-counter-text\"><\/div>\r\n                            <\/div>\r\n\t\t\t\t\t\t                    <\/div>\r\n                    <textarea id=\"daexthefup-comment-textarea\" class=\"daexthefup-comment-textarea\"\r\n                              placeholder=\"Type your message\"\r\n                              maxlength=\"400\"><\/textarea>\r\n                    <div class=\"daexthefup-comment-buttons-container\">\r\n                        <button class=\"daexthefup-comment-submit daexthefup-button\">Submit<\/button>\r\n                        <button class=\"daexthefup-comment-cancel daexthefup-button\">Cancel<\/button>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n                <div class=\"daexthefup-successful-submission-text\">Thanks for your feedback!<\/div>\r\n\r\n            <\/div>\r\n\r\n\t\t\t","protected":false},"excerpt":{"rendered":"<p>Having a large number of participants reduces the risk of accidently having extreme, or biased, groups. Let&#8217;s find out why.<\/p>\n","protected":false},"author":6,"featured_media":27743,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_helpful_pro_status":1,"_searchwp_excluded":"","inline_featured_image":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[40,32,1207],"tags":[1221],"post_folder":[],"class_list":["post-27742","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-updates","category-ha-blog","category-resources","tag-research-updates"],"acf":[],"jetpack_featured_media_url":"https:\/\/www.hydroassoc.org\/wp-content\/uploads\/2021\/03\/SampleSize.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts\/27742","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/comments?post=27742"}],"version-history":[{"count":0,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/posts\/27742\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/media\/27743"}],"wp:attachment":[{"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/media?parent=27742"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/categories?post=27742"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/tags?post=27742"},{"taxonomy":"post_folder","embeddable":true,"href":"https:\/\/www.hydroassoc.org\/wp-json\/wp\/v2\/post_folder?post=27742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}